Re-emerging reactive sulfur-containing compounds and their unique biological functions

Biosynthesis and biological properties of compounds containing highly reactive, reduced sulfane sulfur.

The covalent modifications of sulfhydryl groups (-SH) may occur through oxidation to mixed disulfides (S-thiolation), S-nitrosylation, as well as persulfide and trisulfide formation. The latter possibilities of -SH group modification connected with compounds containing sulfur called sulfane sulfur are described in this paper. Sulfane sulfur compounds contain a labile, highly reactive sulfur ato...

Sulfur-containing compounds from Clinacanthus siamensis.

Two new sulfur-containing compounds, trans-3-methylsulfonyl-2-propenol (1) and trans-3-methylsulfinyl-2-propenol (2) were isolated together with trans-3-methylthioacrylamide (3), entadamide A (4) and entadamide C (5) from the leaves of Clinacanthus siamensis. The structures were established on the basis of the spectroscopic data. The compounds were tested for antimalarial and antimycobacterial ...

emerging and re-emerging zoonoses

Some nitrogen and sulfur containing compounds as chemotherapeutic agents.

Oxidation of Some Biologially Active and Related Sulfur Containing Compounds

Earlier works on oxidation of sulf ides, thiols, and disulf ides with both chemical and enzymic systems are reviewed. Enzymic oxidations of thiols and disulfides are compared with their chemical oxidations with N2O and H2O2 by the use of unsymmetrical disulf ides, thiolsulfinates and O18_ tracer technique. In both enzymic oxidation and that with N2O, oxidation of disulfides to thiolsulfinates i...